Yes. Millions of tourists visit Marrakech every year, and solo travelers, including women, do very well here. The most common problems are not violent crime but persistent sellers, unofficial “guides” and overcharging. A few habits make a big difference:

• Stay in a well-reviewed riad or hostel. Check recent reviews from solo travelers and ask your host to arrange your airport pickup. The medina’s alleys are confusing at night.
• Agree on taxi prices first. For petit taxis, ask for the meter or settle the price before you get in. Ride-hailing apps also work in the city.
• Be polite but firm in the souks. A calm “La, shukran” (no, thank you) works well. You don’t have to enter a shop or accept tea.
• Ignore unofficial guides. If someone says the street is closed or offers to show you the way, keep walking. If you want a guide, book one through your riad or a trusted tour.
• Dress modestly. Covering shoulders and knees reduces unwanted attention and is appreciated locally.
• Avoid empty alleys late at night. Stick to busy streets and Jemaa el-Fna after dark.
• Keep small bills handy. Cash is useful for taxis, cafes and souks, and it avoids long arguments over change.